DNA is without question the most densely electrically charged molecule in any living organism. It carries an intense negative charge along the length of the molecule due to the presence of phosphate groups.

What I wrote in my previous post is not intended to imply that pathogenic DNA or RNA is "naked" as compared to human DNA. Pathogenic nucleic acids can have proteins which bind to its genome or genomic pieces. However, the histone electrical shielding is much more complete in human DNA, than protein binding would provide for pathogen DNA or RNA.

There is a paper that mentions shielding at jcb.rupress.org/content/93/2/285.full.pdf
which is titled "Participation of Core Histone "Tails" in the
Stabilization of the Chromatin Solenoid". The abstract states: "The inference is that the core histone tail segments function by providing electrostatic shielding of the DNA charge and at the same time bridging adjacent
nucleosomes in the solenoid."

Char